[D-Ala4]-Substance P (4-11) is a modified analog of the octapeptide Substance P (4-11), featuring a D-alanine residue substituted at position 4. This structural modification enhances its resistance to enzymatic degradation, improving stability while preserving bioactivity through interactions with neurokinin-1 (NK-1) receptors. It plays a role in modulating pain signaling, inflammatory responses, and immune functions. Employed in pharmacological research, this analog aids in investigating receptor activation mechanisms and exploring therapeutic potential for pain management and inflammatory disorders.

Chemical Formula: C44H65N11O10S

Molecular Weight: 940.14

Sequence: D-Ala-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2

Purity: From crude to 98%

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Research Use Only