Caspase 1 Substrate 1m (ICE), fluorogenic is a valuable tool for researchers studying caspase - 1, or interleukin - 1β - converting enzyme (ICE). It is a fluorogenic substrate engineered with a specific peptide sequence that caspase - 1 can cleave. When caspase - 1 acts on this substrate, it triggers a release of fluorescence. This property allows for highly sensitive and quantitative detection of caspase - 1 activity in biological samples. Given caspase - 1's key role in inflammation and apoptosis, using this fluorogenic substrate helps in understanding the underlying mechanisms of inflammatory diseases and in screening potential drugs that can modulate caspase - 1 function, contributing to the development of new therapies.

Chemical Formula: C35H41N5O12

Molecular Weight: 723.70

Sequence: Ac-Tyr-Glu-Val-Asp-AMC

Purity: From crude to 98%

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